Meloxicam use can result in gastrointestinal toxicity and bleeding, tinnitus, blinding headaches, rash, very dark or black stool (sign of intestinal bleeding). It has fewer gastrointestinal side effects than diclofenac,[4] piroxicam,[5] naproxen,[6] and perhaps all other NSAIDs which are not COX-2 selective.[4] Although meloxicam does inhibit thromboxane A, it does not appear to do so at levels that would interfere with platelet function.

Veterinary use

Under the brand name Metacam, meloxicam is also used in the veterinary field, most commonly in dogs, but also sees off-label use in other animals such as cattle, cats and exotics, [7][8] however the U.S. Food and Drug Administration sent a Notice of Violation to the manufacturer for its promotional materials which included promotion of the drug for off-label use.[9] In the U.S. the drug is indicated for management of pain and inflammation associated with osteoarthritis in dogs only. In Europe, where the product has been available since the early 1990s, it is also prescribed and licensed for other anti-inflammatory benefits including relief from both acute and chronic pain in dogs. Side effects in animals are similar to those found in humans; the principal side effect is gastrointestinal irritation (vomiting, diarrhea and ulceration). Rarer but important side effects include liver and kidney toxicity.

Since 2003, the oral (liquid) formulations of Metacam have been licensed for use in dogs only,[10] with the January 2005 product insert specifically warning in bold-face type: "Do not use in cats."[11] An injectable formulation for use in dogs was approved by the FDA November 2003,[12] with a formulation for cats, for surgical use only, approved in October, 2004.[13]

In the U.S., per the manufacturer's clinical instructions as of July 2010, injectable Metacam is indicated in operative use with felines as a single, one-time dose only, with specific and repeated warnings not to administer a second dose.[14] In June 2007, a new oral version of Metacam was licensed in Europe for the long-term relief of pain in cats. As of June 2008, Metacam is registered for long term use in cats in Australia, New Zealand, and throughout Europe.

复安慰啊

家园

哎，俺也撞过

某次去开会，在某五星酒店自助餐厅，俺放下一盘子菜，转身准备去拿主食，结果那几乎透明的大玻璃门不知啥时候关上了，可怜俺一头就撞上去了，还好，眼镜没碎，不过严重变形，没法戴了，那一声巨响，引得全餐厅瞩目啊，糗大了……还是当着俺自己单位领导的面，哎……

复【原创】今天杯具了，今天药物中毒了

家园

嗯哪，俺也是受害者啊，比企鹅兄还点背

俺六岁时和俺妹妹(四岁)感冒了，一起去某赤脚医生家去打针，抗生素，好像是庆大霉素还是链霉素来着，估计把成人的药量给俺俩注射了，结果俺落了个二级听力残疾，俺妹妹还稍微好一点，真是无语……

西药一定要注意剂量和禁忌症啊！

复【原创】今天杯具了，今天药物中毒了

家园

我的感觉是