主题：【原创】戳穿中粉的谎言，兼指导中粉如何战斗（3） -- 虽远必诛

920年，胡适罹患糖尿病和肾炎，在北京协和医院采用西医方法，久治不愈，被宣判“死刑”。朋友建议他采用中医方法治疗，胡适勉强应允，不料反而痊愈。结果，胡适又活了40多年，这把胡适推到了一个尴尬的境地。他一方面反对中医，一方面却是中医治好了他的病。在事实面前，胡适只好退而认为“中医不科学，很糊涂，但是能治病”。

1961年他郑重申明：“在三十多年前（即1920年），我曾有小病，有一位学西医的朋友，疑是慢性肾脏炎，后来始知此友的诊断不确。如果我患的真是此病，我不会有三四十年的活动能力了。我并未患过此病。贵友说我有秘方可以治此症，此说全无根据。”又说“有人传说我曾患慢性肾脏炎，为中药治好，——其实都不足信。大概慢性肾脏炎至今似尚未有特效药。”（[5]第10册3689页）1958年（罗尔纲文误作1954年[2]），胡适致余复洋的信中也否认中医的误传，说“其实我一生没有得过糖尿病，当然没有陆仲安治愈我的糖尿病的事。”只是 “曾见他治愈朋友的急性肾脏炎，……（慢性肾脏炎是无法治的，急性肾脏炎，则西医也能治疗）。但我从没有听见陆仲安说他有治糖尿病的方子。”（括号内文字是胡适原文。）（[5]第7册第2671页）他还亲自对胡颂平说：“陆仲安是我的朋友，偶曾吃过他的药；但我没有害过糖尿病，也没有吃过糖尿病的药。” （[5]第10册第3539）

一是说胡适“患痔漏，没有找西医开刀，而到上海找潘老太婆医治。”[2]幸而有胡适日记为证，这个说法是错误的。胡适曾患坐骨直肠脓肿、肛瘘反复发作，使他十分痛苦，日记颇详。1922年7月的发作，是在协和医院由谢元大夫动手术诊治的。7月16日 “陆仲安来诊看说是痔疮，今天谢大夫说不是痔，是一个Ischic Rectal Abscess”（坐骨直肠脓肿——本文作者著）。

[Intervention Review]

Chinese herbal medicines for type 2 diabetes mellitus

Jian Ping Liu1, Mei Zhang2, Weiya Wang2, Sameline Grimsgaard3

1Centre for Evidence-BasedChineseMedicine , BeijingUniversity of ChineseMedicine, Beijing, China. 2WestChinaHospital, Sichuan

University, Chengdu, China. 3National Center for Research in Alternative Medicine, University of Tromso, Tromso, Norway

Contact address: Jian Ping Liu, Centre for Evidence-Based Chinese Medicine , Beijing University of Chinese Medicine, 11 Bei San

Huan Dong Lu, Chaoyang District, Beijing, 100029, China. [email protected] . [email protected].

Editorial group: Cochrane Metabolic and Endocrine Disorders Group.

Publication status and date: Edited (no change to conclusions), published in Issue 1, 2009.

Review content assessed as up-to-date: 17 April 2004.

Citation: Liu JP, Zhang M, Wang W, Grimsgaard S. Chinese herbal medicines for type 2 diabetes mellitus. Cochrane Database of

Systematic Reviews 2002, Issue 3. Art. No.: CD003642. DOI: 10.1002/14651858.CD003642.pub2.

Copyright 2009 The Cochrane Collaboration. Published by JohnWiley & Sons, Ltd.

A B S T R A C T

Background

Traditional Chinese herbal medicines have been used for a long time to treat diabetes, and many controlled trials have been done to

investigate their efficacy.

Objectives

To assess the effects of Chinese herbal medicines in patients with type 2 diabetes mellitus.

Search strategy

We searched the following electronic databases: The Cochrane Library (CENTRAL), the Chinese BioMedical Database, MEDLINE,

EMBASE, and LILACS, combined with hand searches on Chinese journals and conference proceedings. No language restriction was

used.

Selection criteria

Randomised trials of herbal medicines (with at least two months treatment duration) compared with placebo, pharmacological or nonpharmacological

interventions were included.

Data collection and analysis

Data were extracted independently by two reviewers. The methodological quality of trials was evaluated using the parameters of

randomisation, allocation concealment, double blinding, and drop-out rates.Meta-analyses were performed where data were available.

Main results

Sixty-six randomised trials, involving 8302 participants, met the inclusion criteria.Methodological quality was generally low. Sixty-nine

different herbal medicines were tested in the included trials, which compared herbal medicines with placebo, hypoglycaemic drugs, or

herbal medicines plus hypoglycaemic drugs.

Compared with placebo, Holy basil leaves, Xianzhen Pian, Qidan Tongmai, traditional Chinese formulae (TCT), Huoxue Jiangtang

Pingzhi, and Inolter showed significantly hypoglycaemic response. Compared with hypoglycaemic drugs including glibenclamide,

tolbutamide, or gliclazide, seven herbal medicines demonstrated a significant better metabolic control, including Bushen Jiangtang

Chinese herbal medicines for type 2 diabetes mellitus (Review)

Copyright 2009 The Cochrane Collaboration. Published by JohnWiley & Sons, Ltd.

Tang, Composite Trichosanthis, Jiangtang Kang, Ketang Ling, Shenqi Jiangtang Yin, Xiaoke Tang, and Yishen Huoxue Tiaogan. In 29 trials

that evaluated herbal medicines combined with hypoglycaemic drugs, 15 different herbal preparations showed additional better effects

than hypoglycaemic drugs monotherapy. Two herbal therapies combined with diet and behaviour change showed better hypoglycaemic

effects than diet and behaviour change alone. No serious adverse effects from the herbal medicines were reported.

Authors’ conclusions

Some herbal medicines show hypoglycaemic effect sin type 2 diabetes. However, these findings should be carefully interpreted due to

the low methodological quality, small sample size, and limited number of trials. In the light of some positive findings, some herbal

medicines deserve further examination in high-quality trials.

P L A I N L A N G U A G E S U M M A R Y

Chinese herbal medicines for type 2 diabetes mellitus

We are still waiting for firm evidence on Chinese herbal medicines for treatment of non-insulin-dependent diabetes. Although the use

of herbal medicines for treatment of diabetes has a long history especially in the East, current evidence cannot warrant to support the

routine use in clinical practice. This systematic review evaluates the effects of various herbal preparations (including single herbs or

mixtures of different herbs) for treating people with type 2 diabetes. The review shows that some herbal medicines lower blood sugar

and relieving symptoms in patients with diabetes. However, the methodological quality of the clinical trials evaluating these herbs is

generally poor. The analyses also indicate that trials with positive findings are more likely to be associated with exaggerated effects.

However, the trials did not report significant adverse effects. In conclusion, herbal medicines should not be recommended for routine

use in diabetic patients of type 2 diabetes until we get scientifically sound trials. Testing the herbs in larger, well-designed trials is needed

in order to establish the necessary evidence for their use.

Chinese